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Institut de Pharmacologie et de Biologie Structurale

 

A joint institute of CNRS and Paul Sabatier University (University of Toulouse)

The main objective of the Institute is to characterize fundamental mechanisms that control the function of biological systems, by analyzing structure-function relationship of macromolecules, in order to develop pharmacological applications.

A primary objective is the identification and characterization of novel pharmacological targets in the fields of Cancer and Infectious Diseases (Tuberculosis).

The Institute is strongly committed to:

   - Teaching: many IPBS scientists participate in undergraduate, master and doctoral programs of the Université de Toulouse ( in the "Biologie-Santé-Biotechnologie" graduate school of Paul Sabatier University )

   - Technology transfers and industrial partnerships

Departments and Scientific objectives

Major findings

Lab Actualities

 

Thesis

11 fev-  10h
Mathieu Léger
Caractérisation enzymatique de la protéine FadD32 de M. tuberculosis, impliquée dans la biosynthèse des acides mycoliques et cible potentielle d’antituberculeux

more

Auditorium F. Gallais

 

Seminars

 

08  Fev -  11h
Simon Benita
Nanoemulsions, a potential targeted carrier for the treatment of severe diseases
 

more

Salle des Séminaires

 

09  Fev -  11h
Malek Djabali
Polycomb function: from homeosis to cell cycle

more

Auditorium F. Gallais

 

10  Fev -  15h
Emmanuelle Bouveret
Interactions physiques et génétiques entre la réponse stringente et le métabolisme des lipides
 

more

Salle des séminaires

 

18  Fev -  11h
Ludovic Pelosi
Caractérisation structurale et fonctionnelle du transporteur d'ADP/ATP mitochondrial : Bilan des connaissances

more

Salle des séminaires

 

1er Mars-  11h
Franck Perez
An Antibody Phage Display Approach for Cell Biology

more

Salle des séminaires

 

12  Mars-  11h
Guy Thwaites
Does Mycobacterium tuberculosis genotype influence the clinical phenotype of tuberculosis?

more

Salle des séminaires

 

 

 

 

Focus

puce Recent publications

 

Giglia-Mari G, et al. (2009) Differentiation Driven Changes in the Dynamic Organization of Basal Transcription Initiation. PLoS Biol 7(10): e1000220. doi:10.1371/

journal.pbio.1000220

puce more

Antoine Tanne et al.

A murine DC-SIGN homologue contributes to early host defense against Mycobacterium tuberculosis

J. Exp. Med. 2009 206: 2205-2220

puce more

 

puceJobs opportunities

 

Tenured investigator/group leader position in the immunology of bacterial infections

puce more

Two-year postdoctoral postion to work on the structural characterization of mycobacterial polyketide synthases

puce more

puce Press release (in french)

 

 

 

 

Centre National de la Recherche ScientifiqueToulouse University

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Institut de Pharmacologie
et de Biologie Structurale

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