|
Department of « Molecular Mechanisms of
Mycobacterial Infections »
Heads : Mamadou Daffé and Christophe Guilhot
Mycobacterial infections, such as tuberculosis, leprosy or Buruli ulcer, are major public health problems throughout the world. For instance, tuberculosis is responsible for more than 1.5 million deaths and 8 million new cases per year.
The main objectives of this department are :
- to decipher the various molecular aspects of pathogenicity, from the identification of virulence genes of the pathogenic agents to the characterization of the infected host responses, and
- to contribute to the fight against mycobacterial diseases through the characterization of potential drug targets and search of inhibitors of these targets, and the development of new strategies for the discovery of vaccine candidates more efficient than the currently used BCG.
This department is composed of 5 teams with complementary expertises which allow us to tackle the problem of mycobacterial infection from different angles.
|
1
