News
IPBS celebrates Pride Month
IPBS invites its community to embrace gender, sexual and ethnic diversity throughout the year, highlighting its support for the LGBTQIA+
8 June 2023
IPBS
Toulouse
Better understanding towards better therapeutics in Cancer, Infection and Inflammation.
News
Lucas Blanchard is awarded the Paul Sabatier University Prize (Life or Earth Sciences) from the Toulouse Academy of Sciences
Dr Lucas Blanchard received the Paul Sabatier University Prize on June 11th at the Hôtel d’Assézat during the formal session
6 June 2023
Press releases
How PAXX keeps our DNA in check
Monitoring the integrity of DNA is the function of the many repair systems present in our cells, specialized in the
1 June 2023
Press releases
The organisation of carbohydrates on the surface of Mycobacterium tuberculosis facilitates infection
The bacterium Mycobacterium tuberculosis, the agent of human tuberculosis, has developed different strategies to attenuate the immune response developed during
19 May 2023
Agenda
Uncovering exhausted CD8 T cell developmental biology reveals opportunities to improve cancer immunotherapy
IPBS-Toulouse, Online Seminar
PhD thesis defense - Ms.Ophelie Dufrancais
Fernand Gallais Conference room
Featured publications (2022-2023)
Mascarau et al. (2023) Productive HIV-1 infection of tissue macrophages by fusion with infected CD4+ T cells. J Cell Biol 222:e202205103
Viljoen*, Vercellone* et al. (2023) Nanoscale clustering of mycobacterial ligands and DC-SIGN host receptors are key determinants for pathogen recognition. Sci Adv 9(20):eadf9498
Seif-El-Dahan M*, Kefala-Stavridi A*, Frit P*, Hardwick SW* et al. PAXX binding to the NHEJ machinery explains functional redundancy with XLF. Sci Adv 9(22):eadg2834
Voisinne*, Locard-Paulet* et al. (2022) Kinetic proofreading through the multi-step activation of the ZAP70 kinase underlies early T cell ligand discrimination. Nat Immunol 23:1355-1364
Boudehen*, Faucher* et al. (2022) Mycobacterial resistance to zinc poisoning requires assembly of P-ATPase-containing membrane metal efflux platforms. Nat Commun 13: 4731
Mosquera-Restrepo et al. (2022) A M. tuberculosis fingerprint in human breath allows tuberculosis detection. Nat Commun 13: 7751
Planès*, Pinilla*, Santoni*, Hessel*, Passemar* et al. (2022) Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells. Mol Cell 82:2385-2400.e9
Asrir*, Tardiveau*, Coudert*, Laffont*, Blanchard* et al. (2022) Tumor-associated high endothelial venules mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4 combination immunotherapy. Cancer Cell 40:318-334.e9
Demange*, Joly*, Marcoux* et al. (2022) SDR enzymes oxidize specific lipidic alkynylcarbinols into cytotoxic protein-reactive species. Elife 11:e73913
About
the IPBS
The IPBS is a joint research center of the CNRS and the University of Toulouse. Occupying 12,000 m2 in the heart of the main campus of the University of Toulouse III-Paul Sabatier, which offers high-level multidisciplinary training in the fields of science, health and engineering, the IPBS is part of one of the most important scientific research poles in health and biological sciences in France.
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