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IPBS Prestige Seminar series - Cancer Immunity and Immunotherapy

L. Zitvogel

Institut Gustave Roussy, Villejuif, France

My gut feeling: Considering intestinal microbiome for an optimal clinical management of cancer patients

Visit the Zitvogel lab

W. H. Fridman

Centre de recherche des Cordeliers, Paris, France

The impact of plasma cells generated in TLS on the therapeutic response to checkpoint inhibitors

Visit the Fridman lab


F. Mechta-Grigoriou

Institut Curie, Paris, France


Role of stromal heterogeneity in immunosuppression and resistance to immunotherapies

Visit the Mechta-Grigoriou lab


J. Helft

Institut Cochin, Paris, France


Macrophage subsets and T cell immunity in breast cancer

Visit the Helft lab



10h00 - Opening and welcome by Dr. Jean-Philippe Girard

10h10 - Prof. Laurence Zitvogel

10h40 - Prof. Wolf Hervé Fridman

11h10 - Dr. Fatima Mechta-Grigoriou

11h40 - Dr. Julie Helft


Selected publications

  • L. Zitvogel

Routy et al. (2018) Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors Science

Andrews et al. (2021) Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade Nat Med

  • W. H. Fridman

Petitprez et al. (2020) B cells are associated with survival and immunotherapy response in sarcoma Nature

Meylan et al. (2022) Tertiary lymphoid structures generate and propagate anti-tumor antibody-producing plasma cells in renal cell cancer Immunity

  • F. Mechta-Grigoriou

Costa et al. (2018) Fibroblast heterogeneity and immunosuppressive environment in human breast cancer Cancer Cell

Kieffer et al. (2020) Single-cell analysis reveals fibroblast clusters linked to immunotherapy resistance in cancer Cancer Discov

  • J. Helft

Helft et al. (2015) GM-CSF mouse bone marrow cultures comprise a heterogeneous population of CD11c+MHCII+ macrophages and DCs Immunity

Ramos et al. (2022) Tissue-resident FOLR2+ macrophages associate with CD8+ T cell infiltration in human breast cancer Cell


Contacts: |

12 Dec

10:00 - 12:00

Fernand Gallais conference room