The silver medal is awarded to researchers for the originality, quality and importance of their work, recognised at national and international levels.
O. Neyrolles is Director of the Institute of Pharmacology and Structural Biology in Toulouse where he leads a research team working on host-pathogen interactions in tuberculosis.
It was during his studies as an agricultural engineer that he realised that he preferred to see large animals in pastures and small ones under a microscope: he wanted to become a microbiologist. After a thesis in microbiology at the Pasteur Institute, he joined Imperial College in London, where he became interested in mycobacteria, including the most infamous of them all: the tuberculosis bacillus. His team's work aims to characterise the molecular players in the TB bacillus that enable it to colonise its host and thus provide prime targets for new treatments. It also focuses on the immune response of the infected host, with prospects for the development of immunotherapies and new vaccine strategies.
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