News
IPBS Welcomes Professor Martin Welch from the University of Cambridge
From 21 October until the end of December, the Institut de Pharmacologie et Biologie Structurale (IPBS) is proud to host
17 October 2025
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Better understanding towards better therapeutics in Cancer, Infection and Inflammation.
News
A year of Cancer research at IPBS
As part of the Pink October campaign, which promotes awareness of breast cancer prevention, we are showcasing a few highlights
11 October 2025
News
The IPBS participates in a newly funded European research project dedicated to advancing novel immunotherapeutic approaches for combating infectious diseases
The NanoBiCar project is one of 45 initiatives selected from 1,110 proposals and funded by the European Innovation Council
3 October 2025
Press releases
A weak point of the TB bacillus identified
In a study published in PNAS, scientists reveal that the survival of the bacterium responsible for tuberculosis, Mycobacterium tuberculosis, depends
22 September 2025
Agenda
HDR Defense - Dr. Delphine Milhas
Fernand Gallais Conference room
10th IPBS Student Symposium
Auditorium Marthe Condat
PhD thesis defense - Ms. Natacha Faivre
Fernand Gallais Conference room
Featured publications (2024-2025)
Frit*, Amin*, Zahid*, Barboule* et al. (2025) Structural and functional insights into the interaction between Ku70/80 and Pol X family polymerases in NHEJ. Nat Commun 16(1):4208
Blanchard*, Vina* et al. (2025) Fc-optimized anti-CTLA-4 antibodies increase tumor-associated high endothelial venules and sensitize refractory tumors to PD-1 blockade. Cell Rep Med
Le Mouëllic et al. (2025) Inorganic sulfate is critical for Mycobacterium tuberculosis lung tissue colonization and redox balance. Proc Natl Acad Sci USA 122 (39) e2503966122
de Caro et al. (2025) New effective and less painful high frequency electrochemotherapy protocols: From optimization on 3D models to pilot study on veterinary patients. J Control Release 381:113592
Gorse*, Plessis*, Wearne*, Paradis*, Pinilla*, Chua* et al. (2025) Portimine A toxin causes skin inflammation through ZAKα-dependent NLRP1 inflammasome activation. EMBO Mol Med DOI: 10.1038/s44321-025-00197-4
Kralj et al. (2025) Dynamically assembling magnetic nanochains as new generation of swarm-type magneto-mechanical nanorobots affecting biofilm integrity. Adv Healthc Mater DOI: 10.1002/adhm.202403736
Gavalda*, Faille*, Fioccola* et al. (2024) Catalytic cycle of type II 4´-phosphopantetheinyl transferases. ACS Catalysis DOI: 10.1021/acscatal.3c06249
Verdys et al. (2024) Ezrin, radixin, and moesin are dispensable for macrophage migration and cortex mechanics. EMBO J DOI: 10.1038/s44318-024-00173-7
Schmitt*, Duval* et al. (2024) TL1A is an epithelial alarmin that cooperates with IL-33 for initiation of allergic airway inflammation. J Exp Med 221 (6): e20231236
Rozario*, Pinilla* et al. (2024) Mechanistic basis for potassium efflux–driven activation of the human NLRP1 inflammasome. Proc Natl Acad Sci USA 121 (2) e2309579121
Bossaert*, Moreno* et al. (2024) Identification of the main barriers to Ku accumulation in chromatin. Cell Rep DOI: 10.1016/j.celrep.2024.114538
Kougkolos et al. (2024) Skin electroporation for transdermal drug delivery: Electrical measurements, numerical model and molecule delivery. J Control Release 367:235-247
About
the IPBS
The IPBS is a joint research center of the CNRS and the University of Toulouse. Occupying 12,000 m2 in the heart of the main campus of the University of Toulouse III-Paul Sabatier, which offers high-level multidisciplinary training in the fields of science, health and engineering, the IPBS is part of one of the most important scientific research poles in health and biological sciences in France.
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CNRS International Actions
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European grants
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