News
Celebrating Diversity and Inclusion at IPBS – Pride Month 2025
For the third consecutive year, the IPBS proudly reaffirms its commitment to fostering an inclusive, respectful, and supportive environment for
3 June 2025
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Better understanding towards better therapeutics in Cancer, Infection and Inflammation.
Press releases
Blood vessels fighting cancer: development of a treatment that enhances the effectiveness of immunotherapy by increasing the entry of ‘killer’ lymphocytes into tumors
Immunotherapy represents a true revolution in cancer treatment. With immunotherapy, some patients with previously incurable cancers go into remission and
3 June 2025
Press releases
Adjusting for better sealing: the function of DNA polymerases in repairing DNA double-strand breaks
The most serious damage to the DNA molecule is the simultaneous breaking of its two component strands. An international collaboration
13 May 2025
News
Call for Post-doctoral fellows – 2025
The Institute of Pharmacology and Structural Biology (IPBS) of Toulouse, France, is seeking motivated postdoctoral researchers to apply for Marie
23 April 2025
Agenda
Mini Symposium | The role of platelets during inflammation and infection
IPBS-Toulouse, Seminar room
PhD Thesis defense - Ms. Lucie Gelon
Fernand Gallais Conference room
Prestigious Lecture by Dr. Manjula Reddy: Bacterial Cell Walls
Fernand Gallais Conference room
Prestigious Lecture by Dr. Ronen Alon: Leukocyte Trafficking in Inflammation and Metastasis
Fernand Gallais Conference room
Featured publications (2024-2025)
Frit*, Amin*, Zahid*, Barboule* et al. (2025) Structural and functional insights into the interaction between Ku70/80 and Pol X family polymerases in NHEJ. Nat Commun 16(1):4208
Blanchard*, Vina* et al. (2025) Fc-optimized anti-CTLA-4 antibodies increase tumor-associated high endothelial venules and sensitize refractory tumors to PD-1 blockade. Cell Rep Med
de Caro et al. (2025) New effective and less painful high frequency electrochemotherapy protocols: From optimization on 3D models to pilot study on veterinary patients. J Control Release 381:113592
Gorse*, Plessis*, Wearne*, Paradis*, Pinilla*, Chua* et al. (2025) Portimine A toxin causes skin inflammation through ZAKα-dependent NLRP1 inflammasome activation. EMBO Mol Med DOI: 10.1038/s44321-025-00197-4
Kralj et al. (2025) Dynamically assembling magnetic nanochains as new generation of swarm-type magneto-mechanical nanorobots affecting biofilm integrity. Adv Healthc Mater DOI: 10.1002/adhm.202403736
Gavalda*, Faille*, Fioccola* et al. (2024) Catalytic cycle of type II 4´-phosphopantetheinyl transferases. ACS Catalysis DOI: 10.1021/acscatal.3c06249
Verdys et al. (2024) Ezrin, radixin, and moesin are dispensable for macrophage migration and cortex mechanics. EMBO J DOI: 10.1038/s44318-024-00173-7
Schmitt*, Duval* et al. (2024) TL1A is an epithelial alarmin that cooperates with IL-33 for initiation of allergic airway inflammation. J Exp Med 221 (6): e20231236
Rozario*, Pinilla* et al. (2024) Mechanistic basis for potassium efflux–driven activation of the human NLRP1 inflammasome. Proc Natl Acad Sci USA 121 (2) e2309579121
Bossaert*, Moreno* et al. (2024) Identification of the main barriers to Ku accumulation in chromatin. Cell Rep DOI: 10.1016/j.celrep.2024.114538
Kougkolos et al. (2024) Skin electroporation for transdermal drug delivery: Electrical measurements, numerical model and molecule delivery. J Control Release 367:235-247
About
the IPBS
The IPBS is a joint research center of the CNRS and the University of Toulouse. Occupying 12,000 m2 in the heart of the main campus of the University of Toulouse III-Paul Sabatier, which offers high-level multidisciplinary training in the fields of science, health and engineering, the IPBS is part of one of the most important scientific research poles in health and biological sciences in France.
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