IPBS-Toulouse

Publications

2025

  • Patil, KV., Sanz, NC., Mak, KH., Yang, W., Annusver, K., Makkar, J., Grommisch, D., Lei, L., Sharma, P., Driskell, RR., Kasper M, Genander M. (2025). The citrullinating enzyme PADI4 governs progenitor cell proliferation and translation in developing hair follicles. Sci Adv. 2025 Sep 12;11(37):eadx4511. doi: 10.1126/sciadv.adx4511. Epub 2025 Sep 12. PMID: 40938992; PMCID: PMC12429026. 
  • Tomita, T., Sharma, P., Hiratsuka, S. (2025). Citrullination in tumor metastasis, inside and outside the cells. Cancer Sci. Published online September 14, 2025. doi:10.1111/cas.70197

2024

  • Boissière-Michot, F., Chateau, MC., Thézenas, S., Lafont, V., Crapez, E., Sharma, P., Bobrie, A., Roger, P., Guiu, S., Jacot, W. (2024). Prognostic value of tertiary lymphoid structures in triple-negative breast cancer: integrated analysis with the tumor microenvironment and clinicopathological features. Front Immunol, 15 : 1507371. doi : 10.3389/fimmu.2024.1507371. 
  • Villanueva-Cañas, J.L., Fernandez-Fuentes, N., Saul, D., Kosinsky, R.L., Teyssier, C., Rogalska, M.E., Pérez, F.P., Oliva, B., Notredame, C., Beato, M. & Sharma, P. (2024). Evolutionary analysis reveals the role of a non-catalytic domain of PADI2 in transcriptional regulation. iScience, doi: https://doi.org/10.1016/j.isci.2024.109584. 

2023

  • Christophorou, MA., Sharma, P., Zhang, X. (2023). Citrullination: new tricks for an old mod. Philos Trans R Soc Lond B Biol Sci, 378:20220235. 

2021

  • Beato, M., Sharma, P. (2021). Peptidyl Arginine Deiminase 2 (PADI2)-mediated Arginine Citrullination modulates Transcription in Cancer. Int J Mol Sci, 21,1351

2019

  • Sharma, P., Lioutas, A., Fernandez-Fuentes, N., Quilez, J., Carbonell-Caballero, J., Wright, R. H. G., Di Vona, C., Le Dily, F., Schüller, R., Eick, D., Oliva, B., & Beato, M. (2019). Arginine citrullination at the C-terminal domain controls RNA Polymerase II transcription. Mol Cell, 73, 84-96
  • Le Dily, F., Vidal, E., Cuartero, Y., Quilez, J., Nacht, A. S., Vicent, G. P., Carbonell-Caballero, J., Sharma, P., Villanueva-Cañas, J. L., Ferrari, R., De Llobet, L. I., Verde, G., Wright, R. H. G., & Beato, M. (2019). Hormone Control Regions mediate opposing steroid receptor-dependent genome organizations. Genome Res, 29;29-39

2018

  • Kumar, A., Sharma, P., Gomar-Alba, M., Shcheprova, Z., Daulny, A., Sanmartín, T., Matucci, I., Funaya, C., Beato, M., & Mendoza, M. (2018). Daughter-Cell-specific modulation of nuclear pore complexes controls cell cycle entry during asymmetric division. Nat Cell Biol, 4, 432-442

2016

  • Nacht, A. S., Pohl, A., Zaurin, R., Soronellas, D., Quilez, J., Sharma, P., Wright, R. H., Beato, M., & Vicent, G. P. (2016). Hormone-induced repression of genes requires BRG1-mediated H1.2 deposition at target promoters. EMBO J, 35, 1822–1843

2014

  • Sharma, P., Garg, G., Kumar, A., Mohammad, F., Kumar, S. R., Tanwar, V. S., Sati, S., Sharma, A., Karthikeyan, G., Brahmachari, V., & Sengupta, S. (2014). Genome wide DNA methylation profiling for epigenetic alteration in coronary artery disease patients. Gene, 541, 31–40

2012

  • Sharma, P., Azebi, S., England, P., Christensen, T., Møller-Larsen, A., Petersen, T., Batsché, E., & Muchardt, C. (2012). Citrullination of histone H3 interferes with HP1-mediated transcriptional repression. PLoS Genet, 8, e1002934

2010

  • Halder, R., Halder, K., Sharma, P., Garg, G., Sengupta, S., & Chowdhury, S. (2010). Guanine quadruplex DNA structure restricts methylation of CpG dinucleotides genome-wide. Mol bioSystems, 6, 2439–2447

2008

  • Sharma, P., Kumar, J., Garg, G., Kumar, A., Patowary, A., Karthikeyan, G., Ramakrishnan, L., Brahmachari, V., & Sengupta, S. (2008). Detection of altered global DNA methylation in coronary artery disease patients. DNA Cell Biol, 27, 357–365

2006

  • Sharma, P., Senthilkumar, R. D., Brahmachari, V., Sundaramoorthy, E., Mahajan, A., Sharma, A., & Sengupta, S. (2006). Mining literature for a comprehensive pathway analysis: a case study for retrieval of homocysteine related genes for genetic and epigenetic studies. Lipids Health Dis, 5, 1

2005

  • Kumar, J., Das, S. K., Sharma, P., Karthikeyan, G., Ramakrishnan, L., & Sengupta, S. (2005). Homocysteine levels are associated with MTHFR A1298C polymorphism in Indian population. J Hum Genet, 50, 655–663