On April 7, at the Sorano Theatre, Mathilde Lacombe will represent IPBS in the regional final of MT180

In Catherine Muller’s team, Mathilde Lacombe’s PhD project aims to investigate the role of androgens produced by peri-prostatic adipose tissue and bone marrow, using human samples, as an alternative source of androgens that may promote prostate cancer progression.

More specifically, this work seeks to determine to what extent these local androgen sources contribute to the persistence of androgen signaling, and thereby to tumor progression as well as resistance to treatment, both at the level of the primary tumor and in bone metastases.