Dr. Guilhot was awarded a PhD in Microbiology from University Paris 7 in 1994 and was a postdoctoral researcher in the group of Pr. J. Beckwith at Harvard Medical School from 1994 to 1995.
In 1996, he got a position at the Pasteur Institute (Paris) and joined the group of Pr. B. Gicquel to develop genetic approaches to explore the biology and pathogenicity of tuberculosis bacilli. He moved to the Institute of Pharmacology and Structural Biology (Toulouse) in 2000 to start the Molecular Mycobacterial Pathogenesis Team through the ATIP-Avenir young researcher program. Since 2001, Dr. Guilhot has become a permanent employee of the Centre National de la Recherche Scientifique (CNRS).
He assumed the position of Co-Chair of the Department of Molecular Mechanisms of Mycobacterial Infections and member of the IPBS executive committee from 2009 to 2015. He stepped down from his Chair’s position in 2015 and now concentrates on his research work on the evolution and mechanisms of pathogenesis of tuberculosis bacilli. His research programs continue to be supported by funding from FRM, National Research Agency, the EU, the Bettencourt Schueller Foundation, MSDAVENIR and the Bill & Melinda Gates Foundation.