Creation of the Trans-NMDA LabCom: An innovative consortium to treat post-traumatic stress disorder
The IPBS and its partners launch the Trans-NMDA Joint Laboratory to develop new therapies for neuropsychiatric diseases.
The Institute of Pharmacology and Structural Biology (IPBS – CNRS/UT3) is delighted to announce the launch of the Trans-NMDA Joint Laboratory (LabCom). This ambitious project is the result of a collaboration between the IPBS, the Toulouse-based laboratories LHFA (Laboratory of Fundamental and Applied Heterochemistry) and CRCA (Research Center on Animal Cognition), as well as the biopharmaceutical company Rest Therapeutics. It aims to develop innovative therapies to treat neuropsychiatric disorders such as post-traumatic stress disorder (PTSD) and Alzheimer’s disease.
PTSD affects approximately 3.9% of the global population at some point in their lives, and its management remains a major public health challenge. The Trans-NMDA LabCom is committed to gaining a deeper understanding of this condition and exploring new therapeutic solutions based on memantine derivatives, an NMDA receptor antagonist with neuroprotective properties.
This joint laboratory brings together unique expertise, led notably by Dr. Franck Talmont (IPBS), in collaboration with Drs. Emmanuel Gras (LHFA) and Lionel Moulédous, as well as Prof. Bruno Guiard (CRCA), specialists in NMDA receptors and neuropsychiatric disorders. By structuring an integrated pharmacology hub, the Trans-NMDA LabCom will cover the entire process of developing new compounds, from their synthesis to their pharmacological evaluation in vitro and in vivo.
This initiative paves the way for new strategic collaborations within IPBS and beyond, with the ambition of advancing research and the development of innovative treatments for neuropsychiatric and neurodegenerative diseases with an inflammatory component. IPBS and its partners hope this project will represent a decisive step toward major scientific and clinical breakthroughs.
Contact presse : Françoise Viala | Communication@ipbs.fr
Contact chercheur : Franck Talmont | Franck.Talmont@ipbs.fr