Publications

2024

Cronin S, de Vries-Egan A, Vahlas Z, Czernikier A, Melucci C, Pereyra Gerber P, O’Neil T, Gloss B, Sharabas M, Turk G, Verollet C, Balboa L, Palmer S, Duette G. The immunosuppressive Tuberculosis-associated microenvironment inhibits viral replication and promotes HIV-1 latency in CD4+ T cells. iScience. 2024. In Press

Verdys P, Rey Barroso J, Girel A, Vermeil J, Bergert M, Sanchez T, Métais A, Mangeat T, Bellard E, Bigot C, Astarie-Dequeker C, Labrousse A, Girard J-P, Maridonneau-Parini I, Vérollet C, Lagarrigue F, Diz-Muñoz A, Heuvingh J, Piel M, Du Roure O, Le Cabec V, Carréno S, Poincloux R. Ezrin, radixin, and Moesin are dispensable for macrophage migration and cellular cortex mechanics. EMBO J. 2024. In Press

Rey-Barroso J., O. Dufrançais O. and Vérollet C. Tunneling Nanotubes in Myeloid Cells: Perspectives for Health and Infectious Diseases. Springer Nature (Book Chapter 17), Results Cell Differentiation, Vol. 73, 2024

Dufrancais O, Verdys P, Métais A, Juzans M, Sanchez T, Bergert M, Plozza M, Halper J, Panebianco CJ, Mascarau R, Gence R, Arnaud G, Ben Neji M, Maridonneau-Parini I, Le Cabec V, Boerckel JD, Pavlos NJ, Diz-Muñoz A, Lagarrigue F, Blin-Wakkach C, Carréno S, Poincloux R, Burkhardt JK, Raynaud-Messina B, Vérollet C. Moesin activation controls bone resorption and tunneling nanotube-dependent osteoclast fusion. bioRxiv [Preprint]. 2024 May 15:2024.05.13.593799. doi: 10.1101/2024.05.13.593799

Gilbert T, Gorlt C, Barbier M, Duployer B, Plozza M, Dufrancais O, Martet LE, Dalbard E, Segot L, Tenailleau C, Haren L, Vérollet C, Bierkamp C, Merdes A. Loss of ninein interferes with osteoclast formation and causes premature ossification. eLife. 2024. 13:e93457

Kumari R, Ven K, Chastney M, Peränen J, Aaron J, Almeida-Souza L, Kremneva E, Poincloux R, Chez TL, Gunning PW, Ivaska J, Lappalainen P. Specialized actin nanoscale layers control focal adhesion turnover. Nat. Comm. 2024. 15(1)2047

Lou E, Verollet C, Winkler F, Zurzolo C, Valdebenito-Silva S, Eugenin E. Tunneling nanotubes and tumor microtubes – Emerging data on their roles in intercellular communication and pathophysiology: Summary of an international FASEB Catalyst Conference October  2023. FASEB J. 2024. 38(5):e23514.

Faivre N, Verollet C, Dumas F. The chemokine receptor CCR5: multi-faceted hook for HIV-1. Retrovirology. 2024. 21(1):2.

Rey-Barroso J, Munaretto A, Rouquie N, Mougel A, Chassa M, Gadat S, Dewingle O, Poincloux R, Cadot S, Ysebaert L, Quillet-Mary A, Dupré L. Lymphocyte migration and retention properties affected by ibrutinib in chronic lymphocytic leukemia. Haematologica. 2024. 109(3):809-823

2023

Maio M, Joly M, Vahlas Z, Barros J, Marín Franco J, Genoula M, Monard S, Vecchione M, Fuentes F, Polo Virginia G, Quiroga M, Vermeulen M, Argüello RJ, Inwentarz S, Musella R, Ciallella L, Montaner P González, Palmero D, Villarino G, del Carmen Sasiain M, Neyrolles O, Verollet C^*, Balboa L^*,# Elevated glycolytic metabolism of monocytes limits the generation of HIF-1α-driven migratory dendritic cells in tuberculosis Elife. 2023 12:RP89319. https://doi.org/10.7554/eLife.89319.1

Mascarau R, B. Raynaud-Messina, C. Vérollet. Macrophage infection by fusion with HIV-1 infected lymphocytes: Catch meto fuse. Med Sci. Aug-Sep;39(8-9):602-605. doi: 10.1051/medsci/2023098. Epub 2023 Sep 11. PMID: 37695146 French

Affannoukoué K, S. Labouesse, G. Maire, I. Gallais, J. Savatier, M. Allain, M. Rasedujjaman, L. Legoff, J. Idier, R. Poincloux, F. Pelletier, C. Leterrier, T. Mangeat, A. Sentenac. Super-resolved total internal reflextion fluorescence microscopy using random illuminations, TIRF-RIM. Optica, 2023, 10(8) 1009-1017

Mascarau, R., M. Woottum, L. Fromont, R. Gence, V. Cantaloube-Ferrieu, Z. Vahlas, K. Lévêque, F. Bertrand, T. Beunon, A. Métais, H. El Costa, N. Jabrane-Ferrat, Y. Gallois, N. Guibert, J.-L. Davignon, G. Favre, I. Maridonneau-Parini, R. Poincloux, B. Lagane, S. Bénichou, B. Raynaud-Messina, and C. Vérollet. 2023. Productive HIV-1 infection of tissue macrophages by fusion with infected CD4+ T cells. J Cell Biol. 2023 (5) e202205103  –  Among the eleven of the articles published in the last year that most interested our readers https://rupress.org/jcb/collection/22023/The-Year-in-Cell-Biology-2023?nbd=40786096593&nbd_source=campaigner&utm_source=Email_marketing&utm_campaign=YiCB_2023&cmp=1&utm_medium=HTMLEmail

2022

Dupont, M., S. Rousset, T.-P.V. Manh, S.C. Monard, K. Pingris, S. Souriant, Z. Vahlas, T. Velez, R. Poincloux, I. 1st Maridonneau-Parini, O. Neyrolles, G. Lugo-Villarino, and C. Vérollet. 2022. Dysregulation of the IFN-I signaling pathway by Mycobacterium tuberculosis leads to exacerbation of HIV-1 infection of macrophages. J Leukoc Biol. 112:1329–1342.

Han, M., M. Woottum, R. Mascarau, Z. Vahlas, C. Verollet, and S. Benichou. 2022. Mechanisms of HIV-1 cell-to-cell transfer to myeloid cells. J Leukoc Biol. 112:1261–1271.

Jasnin, M., J. Hervy, S. Balor, A. Bouissou, A. Proag, R. Voituriez, J. Schneider, T. Mangeat, I. Maridonneau-Parini, W. Baumeister, S. Dmitrieff, and R. Poincloux. 2022. Elasticity of podosome actin networks produces nanonewton protrusive forces. Nat Commun. 13:3842.

Portes, M., T. Mangeat, N. Escallier, O. Dufrancais, B. Raynaud-Messina, C. Thibault, I. Maridonneau-Parini, C. Vérollet, and R. Poincloux. 2022. Nanoscale architecture and coordination of actin cores within the sealing zone of human osteoclasts. Elife. 11.

Santoni, K., D. Pericat, L. Gorse, J. Buyck, M. Pinilla, L. Prouvensier, S. Bagayoko, A. Hessel, S.A. Leon-Icaza, E. Bellard, S. Mazères, E. Doz-Deblauwe, N. Winter, C. Paget, J.-P. Girard, C.T.N. Pham, C. Cougoule, R. Poincloux, M. Lamkanfi, E. Lefrançais, E. Meunier, and R. Planès. 2022. Caspase-1-driven neutrophil pyroptosis and its role in host susceptibility to Pseudomonas aeruginosa. PLoS Pathog. 18:e1010305.

2021

Benet, S., C. Gálvez, F. Drobniewski, I. Kontsevaya, L. Arias, M. Monguió-Tortajada, I. Erkizia, V. Urrea, R.-Y. Ong, M. Luquin, M. Dupont, J. Chojnacki, J. Dalmau, P. Cardona, O. Neyrolles, G. Lugo-Villarino, C. Vérollet, E. Julián, H. Furrer, H.F. Günthard, P.R. Crocker, G. Tapia, F.E. Borràs, J. Fellay, P.J. McLaren, A. Telenti, P.-J. Cardona, B. Clotet, C. Vilaplana, J. Martinez-Picado, and N. Izquierdo-Useros. 2021. Dissemination of Mycobacterium tuberculosis is associated to a SIGLEC1 null variant that limits antigen exchange via trafficking extracellular vesicles. J Extracell Vesicles. 10:e12046.

Bernard-Raichon, L., A. Colom, S.C. Monard, A. Namouchi, M. Cescato, H. Garnier, S.A. Leon-Icaza, A. Métais, A. Dumas, D. Corral, N. Ghebrendrias, P. Guilloton, C. Vérollet, D. Hudrisier, A. Remot, P. Langella, M. Thomas, C. Cougoule, O. Neyrolles, and G. Lugo-Villarino. 2021. A Pulmonary Lactobacillus murinus Strain Induces Th17 and RORγt(+) Regulatory T Cells and Reduces Lung Inflammation in Tuberculosis. J Immunol. 207:1857–1870.

Dufrançais, O., R. Mascarau, R. Poincloux, I. Maridonneau-Parini, B. Raynaud-Messina, and C. Vérollet. 2021. Cellular and molecular actors of myeloid cell fusion: podosomes and tunneling nanotubes call the tune. Cell Mol Life Sci. 78:6087–6104.

Gelis, A., J. Morel, B. Amara, C. Mauri, H. Rouays, C. Verollet, I. Almeras, N. Frasson, A. Dupeyron, I. Laffont, J.-P. Daures, and C. Herlin. 2021. “Doctor, how long will it take?” Results from an historical cohort on surgical pressure ulcer healing delay and related factors in persons with spinal cord  injury. J Tissue Viability. 30:237–243.

Mangeat, T., S. Labouesse, M. Allain, A. Negash, E. Martin, A. Guénolé, R. Poincloux, C. Estibal, A. Bouissou, S. Cantaloube, E. Vega, T. Li, C. Rouvière, S. Allart, D. Keller, V. Debarnot, X.B. Wang, G. Michaux, M. Pinot, R. Le Borgne, S. Tournier, M. Suzanne, J. Idier, and A. Sentenac. 2021. Super-resolved live-cell imaging using random illumination microscopy. Cell Rep Methods. 1:100009.

Pires, D., M. Calado, T. Velez, M. Mandal, M.J. Catalão, O. Neyrolles, G. Lugo-Villarino, C. Vérollet, J.M. Azevedo-Pereira, and E. Anes. 2021. Modulation of Cystatin C in Human Macrophages Improves Anti-Mycobacterial Immune Responses to Mycobacterium tuberculosis Infection and Coinfection With HIV. Front Immunol. 12:742822.

Tertrais, M., C. Bigot, E. Martin, R. Poincloux, A. Labrousse, and I. Maridonneau-Parini. 2021. Phagocytosis is coupled to the formation of phagosome-associated podosomes and a transient disruption of podosomes in human macrophages. Eur J Cell Biol. 100:151161.

2020

Accarias, S., T. Sanchez, A. Labrousse, M. Ben-Neji, A. Boyance, R. Poincloux, I. Maridonneau-Parini, and V. Le Cabec. 2020. Genetic engineering of Hoxb8-immortalized hematopoietic progenitors – a potent tool to study macrophage tissue migration. J Cell Sci. 133:jcs236703.

Dupont, M., G. Lugo-Villarino, and C. Vérollet. 2020a. [The Siglec-1 receptor: bridging the infectious synergy between Mycobacterium tuberculosis and HIV-1]. Med Sci (Paris). 36:855–858.

Dupont, M., S. Souriant, L. Balboa, T.-P. Vu Manh, K. Pingris, S. Rousset, C. Cougoule, Y. Rombouts, R. Poincloux, M. Ben Neji, C. Allers, D. Kaushal, M.J. Kuroda, S. Benet, J. Martinez-Picado, N. Izquierdo-Useros, M.D.C. Sasiain, I. Maridonneau-Parini, O. Neyrolles, C. Vérollet, and G. Lugo-Villarino. 2020b. Tuberculosis-associated IFN-I induces Siglec-1 on tunneling nanotubes and favors HIV-1 spread in macrophages. Elife. 9.

Genoula, M., J.L. Marín Franco, M. Maio, B. Dolotowicz, M. Ferreyra, M.A. Milillo, R. Mascarau, E.J. Moraña, D. Palmero, M. Matteo, F. Fuentes, B. López, P. Barrionuevo, O. Neyrolles, C. Cougoule, G. Lugo-Villarino, C. Vérollet, M.D.C. Sasiain, and L. Balboa. 2020. Fatty acid oxidation of alternatively activated macrophages prevents foam cell formation, but Mycobacterium tuberculosis counteracts this process via HIF-1α  activation. PLoS Pathog. 16:e1008929.

Guérit, D., P. Marie, A. Morel, J. Maurin, C. Verollet, B. Raynaud-Messina, S. Urbach, and A. Blangy. 2020. Primary myeloid cell proteomics and transcriptomics: importance of β-tubulin isotypes for osteoclast function. J Cell Sci. 133.

Marín Franco, J.L., M. Genoula, D. Corral, G. Duette, M. Ferreyra, M. Maio, M.B. Dolotowicz, O.E. Aparicio-Trejo, E. Patiño-Martínez, A. Charton, A. Métais, F. Fuentes, V. Soldan, E.J. Moraña, D. Palmero, M. Ostrowski, P. Schierloh, C. Sánchez-Torres, R. Hernández-Pando, J. Pedraza-Chaverri, Y. Rombouts, D. Hudrisier, E. Layre, C. Vérollet, I. Maridonneau-Parini, O. Neyrolles, M.D.C. Sasiain, G. Lugo-Villarino, and L. Balboa. 2020. Host-Derived Lipids from Tuberculous Pleurisy Impair Macrophage Microbicidal-Associated Metabolic Activity. Cell Rep. 33:108547

Mascarau, R., F. Bertrand, A. Labrousse, I. Gennero, R. Poincloux, I. Maridonneau-Parini, B. Raynaud-Messina, and C. Vérollet. 2020. HIV-1-Infected Human Macrophages, by Secreting RANK-L, Contribute to Enhanced Osteoclast Recruitment. Int J Mol Sci. 21.

2019

van den Dries, K., S. Linder, I. Maridonneau-Parini, and R. Poincloux. 2019. Probing the mechanical landscape – new insights into podosome architecture and mechanics. J Cell Sci. 132:jcs236828.

Lugo-Villarino, G., C. Cougoule, E. Meunier, Y. Rombouts, C. Vérollet, and L. Balboa. 2019. Editorial: The Mononuclear Phagocyte System in Infectious Disease. Front Immunol. 10:1443.

Morel, J., C. Herlin, B. Amara, C. Mauri, H. Rouays, C. Verollet, I. Almeras, N. Frasson, A. Dupeyron, C. Jourdan, J.-P. Daures, and A. Gelis. 2019. Risk factors of pelvic pressure ulcer recurrence after primary skin flap surgery in people with spinal cord injury. Ann Phys Rehabil Med. 62:77–83.

Raynaud-Messina, B., C. Verollet, and I. Maridonneau-Parini. 2019. The osteoclast, a target cell for microorganisms. Bone. 127:315–323.

Souriant, S., L. Balboa, M. Dupont, K. Pingris, D. Kviatcovsky, C. Cougoule, C. Lastrucci, A. Bah, R. Gasser, R. Poincloux, B. Raynaud-Messina, T. Al Saati, S. Inwentarz, S. Poggi, E.J. Moraña, P. González-Montaner, M. Corti, B. Lagane, I. Vergne, C. Allers, D. Kaushal, M.J. Kuroda, M.D.C. Sasiain, O. Neyrolles, I. Maridonneau-Parini, G. Lugo-Villarino, and C. Vérollet. 2019. Tuberculosis Exacerbates HIV-1 Infection through IL-10/STAT3-Dependent Tunneling Nanotube Formation in Macrophages. Cell Rep. 26:3586-3599

Souriant, S., M. Dupont, O. Neyrolles, I. Maridonneau-Parini, G. Lugo-Villarino, and C. Vérollet. 2019. [Tunneling nanotube formation in HIV-1-infected human macrophages: building bridges for efficient HIV-1 dissemination during co-infection with Mycobacterium  tuberculosis]. Med Sci (Paris). 35:825–827.

Xie, M., H. Leroy, R. Mascarau, M. Woottum, M. Dupont, C. Ciccone, A. Schmitt, B. Raynaud-Messina, C. Vérollet, J. Bouchet, L. Bracq, and S. Benichou. 2019. Cell-to-Cell Spreading of HIV-1 in Myeloid Target Cells Escapes SAMHD1 Restriction. mBio. 10.

2018

Baschieri, F., S. Dayot, N. Elkhatib, N. Ly, A. Capmany, K. Schauer, T. Betz, D.M. Vignjevic, R. Poincloux, and G. Montagnac. 2018. Frustrated endocytosis controls contractility-independent mechanotransduction at clathrin-coated structures. Nat Commun. 9:3825.

Cervero, P., C. Wiesner, A. Bouissou, R. Poincloux, and S. Linder. 2018. Lymphocyte-specific protein 1 regulates mechanosensory oscillation of podosomes and actin isoform-based actomyosin symmetry breaking. Nat Commun. 9:515.

Colado, A., M. Genoula, C. Cougoule, J.L. Marín Franco, M.B. Almejún, D. Risnik, D. Kviatcovsky, E. Podaza, E.E. Elías, F. Fuentes, I. Maridonneau-Parini, F.R. Bezares, H. Fernandez Grecco, M. Cabrejo, C. Jancic, M.D.C. Sasiain, M. Giordano, R. Gamberale, L. Balboa, and M. Borge. 2018. Effect of the BTK inhibitor ibrutinib on macrophage- and γδ T cell-mediated response against Mycobacterium tuberculosis. Blood Cancer J. 8:100.

Cougoule, C., C. Lastrucci, R. Guiet, R. Mascarau, E. Meunier, G. Lugo-Villarino, O. Neyrolles, R. Poincloux, and I. Maridonneau-Parini. 2018. Podosomes, But Not the Maturation Status, Determine the Protease-Dependent 3D Migration in Human Dendritic Cells. Front Immunol. 9:846.

Desvignes, E., A. Bouissou, A. Laborde, T. Mangeat, A. Proag, C. Vieu, C. Thibault, I. Maridonneau-Parini, and R. Poincloux. 2018. Nanoscale Forces during Confined Cell Migration. Nano Lett. 18:6326–6333.

Dupont, M., S. Souriant, G. Lugo-Villarino, I. Maridonneau-Parini, and C. Vérollet. 2018. Tunneling Nanotubes: Intimate Communication between Myeloid Cells. Front Immunol. 9:43.

Genoula, M., J.L. Marín Franco, M. Dupont, D. Kviatcovsky, A. Milillo, P. Schierloh, E.J. Moraña, S. Poggi, D. Palmero, D. Mata-Espinosa, E. González-Domínguez, J.C. León Contreras, P. Barrionuevo, B. Rearte, M.O. Córdoba Moreno, A. Fontanals, A. Crotta Asis, G. Gago, C. Cougoule, O. Neyrolles, I. Maridonneau-Parini, C. Sánchez-Torres, R. Hernández-Pando, C. Vérollet, G. Lugo-Villarino, M.D.C. Sasiain, and L. Balboa. 2018. Formation of Foamy Macrophages by Tuberculous Pleural Effusions Is Triggered by the Interleukin-10/Signal Transducer and Activator of Transcription 3 Axis through ACAT Upregulation. Front Immunol. 9:459.

Gonçalves-de-Albuquerque, C.F., I. Rohwedder, A.R. Silva, A.S. Ferreira, A.R.M. Kurz, C. Cougoule, S. Klapproth, T. Eggersmann, J.D. Silva, G.P. de Oliveira, V.L. Capelozzi, G.G. Schlesinger, E.R. Costa, R. de C.E. Estrela Marins, A. Mócsai, I. Maridonneau-Parini, B. Walzog, P.R. Macedo Rocco, M. Sperandio, and H.C. de Castro-Faria-Neto. 2018. The Yin and Yang of Tyrosine Kinase Inhibition During Experimental Polymicrobial Sepsis. Front Immunol. 9:901.

Gui, P., M. Ben-Neji, E. Belozertseva, F. Dalenc, C. Franchet, J. Gilhodes, A. Labrousse, E. Bellard, M. Golzio, R. Poincloux, I. Maridonneau-Parini, and V. Le Cabec. 2018. The Protease-Dependent Mesenchymal Migration of Tumor-Associated Macrophages as a Target in Cancer Immunotherapy. Cancer Immunol Res. 6:1337–1351.

Le Cabec, V., E. Van Goethem, R. Guiet, and I. Maridonneau-Parini. 2011. [Phagocyte migration: an overview]. Med Sci (Paris). 27:1112–1119.

2017

Bouissou, A., A. Proag, N. Bourg, K. Pingris, C. Cabriel, S. Balor, T. Mangeat, C. Thibault, C. Vieu, G. Dupuis, E. Fort, S. Lévêque-Fort, I. Maridonneau-Parini, and R. Poincloux. 2017. Podosome Force Generation Machinery: A Local Balance between Protrusion at the Core and Traction at the Ring. ACS Nano. 11:4028–4040.

Demy, D.L., M. Tauzin, M. Lancino, V. Le Cabec, M. Redd, E. Murayama, I. Maridonneau-Parini, N. Trede, and P. Herbomel. 2017. Trim33 is essential for macrophage and neutrophil mobilization to developmental or inflammatory cues. J Cell Sci. 130:2797–2807.

Troegeler, A., I. Mercier, C. Cougoule, D. Pietretti, A. Colom, C. Duval, T.-P. Vu Manh, F. Capilla, R. Poincloux, K. Pingris, J. Nigou, J. Rademann, M. Dalod, F.A.W. Verreck, T. Al Saati, G. Lugo-Villarino, B. Lepenies, D. Hudrisier, and O. Neyrolles. 2017. C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells. Proc Natl Acad Sci U S A. 114:E540–E549.

2016

Proag, A., A. Bouissou, C. Vieu, I. Maridonneau-Parini, and R. Poincloux. 2016. Evaluation of the force and spatial dynamics of macrophage podosomes by multi-particle tracking. Methods. 94:75–84.

2015

Alvarez-Zarate, J., H.L. Matlung, T. Matozaki, T.W. Kuijpers, I. Maridonneau-Parini, and T.K. van den Berg. 2015. Regulation of Phagocyte Migration by Signal Regulatory Protein-Alpha Signaling. PLoS One. 10:e0127178.

Balboa, L., J. Barrios-Payan, E. González-Domínguez, C. Lastrucci, G. Lugo-Villarino, D. Mata-Espinoza, P. Schierloh, D. Kviatcovsky, O. Neyrolles, I. Maridonneau-Parini, C. Sánchez-Torres, M. del C. Sasiain, and R. Hernández-Pando. 2015. Diverging biological roles among human monocyte subsets in the context of tuberculosis infection. Clin Sci (Lond). 129:319–330.

Lastrucci, C., V. Baillif, A. Behar, T. Al Saati, M. Dubourdeau, I. Maridonneau-Parini, and C. Cougoule. 2015. Molecular and cellular profiles of the resolution phase in a damage-associated molecular pattern (DAMP)-mediated peritonitis model and revelation of leukocyte  persistence in peritoneal tissues. FASEB J. 29:1914–1929.

Lastrucci, C., A. Bénard, L. Balboa, K. Pingris, S. Souriant, R. Poincloux, T. Al Saati, V. Rasolofo, P. González-Montaner, S. Inwentarz, E.J. Moraña, I. Kondova, F.A.W. Verreck, M. del C. Sasiain, O. Neyrolles, I. Maridonneau-Parini, G. Lugo-Villarino, and C. Cougoule. 2015. Tuberculosis is associated with expansion of a motile, permissive and immunomodulatory CD16(+) monocyte population via the IL-10/STAT3 axis. Cell Res. 25:1333–1351.

Medina, I., C. Cougoule, M. Drechsler, B. Bermudez, R.R. Koenen, J. Sluimer, I. Wolfs, Y. Döring, V. Herias, M. Gijbels, I. Bot, S. de Jager, C. Weber, J. Cleutjens, T.J.C. van Berkel, K.-J. Sikkink, A. Mócsai, I. Maridonneau-Parini, O. Soehnlein, and E.A.L. Biessen. 2015. Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monocyte Recruitment and Intraplaque Motility. Circulation. 132:490–501.

Proag, A., A. Bouissou, T. Mangeat, R. Voituriez, P. Delobelle, C. Thibault, C. Vieu, I. Maridonneau-Parini, and R. Poincloux. 2015. Working together: spatial synchrony in the force and actin dynamics of podosome first neighbors. ACS Nano. 9:3800–3813.

Vérollet, C., V. Le Cabec, and I. Maridonneau-Parini. 2015. HIV-1 Infection of T Lymphocytes and Macrophages Affects Their Migration via Nef. Front Immunol. 6:514.

Vérollet, C., S. Souriant, E. Bonnaud, P. Jolicoeur, B. Raynaud-Messina, C. Kinnaer, I. Fourquaux, A. Imle, S. Benichou, O.T. Fackler, R. Poincloux, and I. Maridonneau-Parini. 2015. HIV-1 reprograms the migration of macrophages. Blood. 125:1611–1622.

Vérollet, C., S. Souriant, B. Raynaud-Messina, and I. Maridonneau-Parini. 2015. [HIV-1 drives the migration of macrophages]. Med Sci (Paris). 31:730–733.

2014

Bouissou, A., C. Vérollet, H. de Forges, L. Haren, Y. Bellaïche, F. Perez, A. Merdes, and B. Raynaud-Messina. 2014. γ-Tubulin Ring Complexes and EB1 play antagonistic roles in microtubule dynamics and spindle positioning. EMBO J. 33:114–128.

Gouzy, A., G. Larrouy-Maumus, D. Bottai, F. Levillain, A. Dumas, J.B. Wallach, I. Caire-Brandli, C. de Chastellier, T.-D. Wu, R. Poincloux, R. Brosch, J.-L. Guerquin-Kern, D. Schnappinger, L.P. Sório de Carvalho, Y. Poquet, and O. Neyrolles. 2014. Mycobacterium tuberculosis exploits asparagine to assimilate nitrogen and resist acid stress during infection. PLoS Pathog. 10:e1003928.

Gui, P., A. Labrousse, E. Van Goethem, A. Besson, I. Maridonneau-Parini, and V. Le Cabec. 2014. Rho/ROCK pathway inhibition by the CDK inhibitor p27(kip1) participates in the onset of macrophage 3D-mesenchymal migration. J Cell Sci. 127:4009–4023.

Labernadie, A., A. Bouissou, P. Delobelle, S. Balor, R. Voituriez, A. Proag, I. Fourquaux, C. Thibault, C. Vieu, R. Poincloux, G.M. Charrière, and I. Maridonneau-Parini. 2014. Protrusion force microscopy reveals oscillatory force generation and mechanosensing activity of human macrophage podosomes. Nat Commun. 5:5343.

Maridonneau-Parini, I. 2014. Podosomes are disrupted in PAPA syndrome. Blood. 123:2597–2599.

Maridonneau-Parini, I. 2014. Control of macrophage 3D migration: a therapeutic challenge to limit tissue infiltration. Immunol Rev. 262:216–231.

Park, H., A. Dovas, S. Hanna, C. Lastrucci, C. Cougoule, R. Guiet, I. Maridonneau-Parini, and D. Cox. 2014. Tyrosine phosphorylation of Wiskott-Aldrich syndrome protein (WASP) by Hck regulates macrophage function. J Biol Chem. 289:7897–7906.

Troegeler, A., C. Lastrucci, C. Duval, A. Tanne, C. Cougoule, I. Maridonneau-Parini, O. Neyrolles, and G. Lugo-Villarino. 2014. An efficient siRNA-mediated gene silencing in primary human monocytes, dendritic cells and macrophages. Immunol Cell Biol. 92:699–708.

Wiesner, C., V. Le-Cabec, K. El Azzouzi, I. Maridonneau-Parini, and S. Linder. 2014. Podosomes in space: macrophage migration and matrix degradation in 2D and 3D settings. Cell Adh Migr. 8:179–191.

2013

Ben Amara, A., L. Gorvel, K. Baulan, J. Derain-Court, C. Buffat, C. Vérollet, J. Textoris, E. Ghigo, F. Bretelle, I. Maridonneau-Parini, and J.-L. Mege. 2013. Placental macrophages are impaired in chorioamnionitis, an infectious pathology of the placenta. J Immunol. 191:5501–5514.

Bochet, L., C. Lehuédé, S. Dauvillier, Y.Y. Wang, B. Dirat, V. Laurent, C. Dray, R. Guiet, I. Maridonneau-Parini, S. Le Gonidec, B. Couderc, G. Escourrou, P. Valet, and C. Muller. 2013. Adipocyte-derived fibroblasts promote tumor progression and contribute to the desmoplastic reaction in breast cancer. Cancer Res. 73:5657–5668.

Marchetti, M., D. Capela, R. Poincloux, N. Benmeradi, M.-C. Auriac, A. Le Ru, I. Maridonneau-Parini, J. Batut, and C. Masson-Boivin. 2013. Queuosine biosynthesis is required for sinorhizobium meliloti-induced cytoskeletal modifications on HeLa Cells and symbiosis with Medicago truncatula. PLoS One. 8:e56043.

Vérollet, C., A. Gallois, R. Dacquin, C. Lastrucci, S.N.M. Pandruvada, N. Ortega, R. Poincloux, A. Behar, C. Cougoule, C. Lowell, T. Al Saati, P. Jurdic, and I. Maridonneau-Parini. 2013. Hck contributes to bone homeostasis by controlling the recruitment of osteoclast precursors. FASEB J. 27:3608–3618.

2012

Ariel, A., I. Maridonneau-Parini, P. Rovere-Querini, J.S. Levine, and H. Mühl. 2012. Macrophages in inflammation and its resolution. Front Immunol. 3:324.

Bouchet, J., C. Hérate, C.A. Guenzel, C. Vérollet, A. Järviluoma, J. Mazzolini, S. Rafie, P. Chames, D. Baty, K. Saksela, F. Niedergang, I. Maridonneau-Parini, and S. Benichou. 2012. Single-domain antibody-SH3 fusions for efficient neutralization of HIV-1 Nef functions. J Virol. 86:4856–4867.

Cougoule, C., E. Van Goethem, V. Le Cabec, F. Lafouresse, L. Dupré, V. Mehraj, J.-L. Mège, C. Lastrucci, and I. Maridonneau-Parini. 2012. Blood leukocytes and macrophages of various phenotypes have distinct abilities to form podosomes and to migrate in 3D environments. Eur J Cell Biol. 91:938–949.

Guiet, R., C. Vérollet, I. Lamsoul, C. Cougoule, R. Poincloux, A. Labrousse, D.A. Calderwood, M. Glogauer, P.G. Lutz, and I. Maridonneau-Parini. 2012. Macrophage mesenchymal migration requires podosome stabilization by filamin A. J Biol Chem. 287:13051–13062.

2011

Botella, H., P. Peyron, F. Levillain, R. Poincloux, Y. Poquet, I. Brandli, C. Wang, L. Tailleux, S. Tilleul, G.M. Charrière, S.J. Waddell, M. Foti, G. Lugo-Villarino, Q. Gao, I. Maridonneau-Parini, P.D. Butcher, P.R. Castagnoli, B. Gicquel, C. de Chastellier, and O. Neyrolles. 2011. Mycobacterial p(1)-type ATPases mediate resistance to zinc poisoning in human macrophages. Cell Host Microbe. 10:248–259.

Guiet, R., E. Van Goethem, C. Cougoule, S. Balor, A. Valette, T. Al Saati, C.A. Lowell, V. Le Cabec, and I. Maridonneau-Parini. 2011. The process of macrophage migration promotes matrix metalloproteinase-independent invasion by tumor cells. J Immunol. 187:3806–3814.

Hawkins, R.J., R. Poincloux, O. Bénichou, M. Piel, P. Chavrier, and R. Voituriez. 2011. Spontaneous contractility-mediated cortical flow generates cell migration in three-dimensional environments. Biophys J. 101:1041–1045.

Labrousse, A.M., E. Meunier, J. Record, A. Labernadie, A. Beduer, C. Vieu, T. Ben Safta, and I. Maridonneau-Parini. 2011. Frustrated phagocytosis on micro-patterned immune complexes to characterize lysosome movements in live macrophages. Front Immunol. 2:51.

Le Cabec, V., E. Van Goethem, R. Guiet, and I. Maridonneau-Parini. 2011. [Phagocyte migration: an overview]. Med Sci (Paris). 27:1112–1119.

Lugo-Villarino, G., C. Vérollet, I. Maridonneau-Parini, and O. Neyrolles. 2011. Macrophage polarization: convergence point targeted by mycobacterium tuberculosis and HIV. Front Immunol. 2:43.

Poincloux, R., O. Collin, F. Lizárraga, M. Romao, M. Debray, M. Piel, and P. Chavrier. 2011. Contractility of the cell rear drives invasion of breast tumor cells in 3D Matrigel. Proc Natl Acad Sci U S A. 108:1943–1948.

Van Goethem, E., R. Guiet, S. Balor, G.M. Charrière, R. Poincloux, A. Labrousse, I. Maridonneau-Parini, and V. Le Cabec. 2011. Macrophage podosomes go 3D. Eur J Cell Biol. 90:224–236.

Vérollet, C., G.M. Charrière, A. Labrousse, C. Cougoule, V. Le Cabec, and I. Maridonneau-Parini. 2011. Extracellular proteolysis in macrophage migration: losing grip for a breakthrough. Eur J Immunol. 41:2805–2813.

2010

Boissan, M., O. De Wever, F. Lizarraga, D. Wendum, R. Poincloux, N. Chignard, C. Desbois-Mouthon, S. Dufour, B. Nawrocki-Raby, P. Birembaut, M. Bracke, P. Chavrier, C. Gespach, and M.-L. Lacombe. 2010. Implication of metastasis suppressor NM23-H1 in maintaining adherens junctions and limiting the invasive potential of human cancer cells. Cancer Res. 70:7710–7722.

Cougoule, C., V. Le Cabec, R. Poincloux, T. Al Saati, J.-L. Mège, G. Tabouret, C.A. Lowell, N. Laviolette-Malirat, and I. Maridonneau-Parini. 2010. Three-dimensional migration of macrophages requires Hck for podosome organization and extracellular matrix proteolysis. Blood. 115:1444–1452.

Labernadie, A., C. Thibault, C. Vieu, I. Maridonneau-Parini, and G.M. Charrière. 2010. Dynamics of podosome stiffness revealed by atomic force microscopy. Proc Natl Acad Sci U S A. 107:21016–21021.

Van Goethem, E., R. Poincloux, F. Gauffre, I. Maridonneau-Parini, and V. Le Cabec. 2010. Matrix architecture dictates three-dimensional migration modes of human macrophages: differential involvement of proteases and podosome-like structures. J Immunol. 184:1049–1061.

Vérollet, C., Y.M. Zhang, V. Le Cabec, J. Mazzolini, G. Charrière, A. Labrousse, J. Bouchet, I. Medina, E. Biessen, F. Niedergang, S. Bénichou, and I. Maridonneau-Parini. 2010. HIV-1 Nef triggers macrophage fusion in a p61Hck- and protease-dependent manner. J Immunol. 184:7030–7039.

 z