How a rogue immune signal fuels a rare skin cancer, and how to shut it down
An international team of researchers has discovered how a molecule normally used by the immune[…]
PA200: A protein that reprograms the immunoproteasome and its activity
The immunoproteasome degrades cellular proteins to generate peptides, including those presented to immune system cells.[…]
IL-33, from inflammation to platelets: towards a better understanding of certain forms of thrombocytopenia
IL-33 is a key cytokine in inflammation, but may also play a role in platelet[…]
A new type of anucleate fat cell involved in blood cell production discovered in human bone marrow
Long considered a passive structural component, bone marrow adipose tissue is now emerging as a[…]
The Werner protein, guardian of the genome: a helping hand for its repair function
A recent discovery sheds new light on the mechanisms underlying Werner syndrome, a rare disorder[…]
Tuberculosis: how the bacterium expels toxic metals to resist the immune system
The tuberculosis bacillus survives inside immune cells by neutralizing toxic metals such as zinc. A[…]
A New Role for IL-33 in Platelet Biology
IPBS is delighted to announce the publication of groundbreaking research led by Dr. Emma Lefrançais[…]
Moesin Protein Controls Bone Remodeling by Regulating Osteoclast Fusion and Function
Researchers at the Institut de Pharmacologie et Biologie Structurale (IPBS) have uncovered a pivotal role[…]
A weak point of the TB bacillus identified
In a study published in PNAS, scientists reveal that the survival of the bacterium responsible[…]
Blood vessels fighting cancer: development of a treatment that enhances the effectiveness of immunotherapy by increasing the entry of ‘killer’ lymphocytes into tumors
Immunotherapy represents a true revolution in cancer treatment. With immunotherapy, some patients with previously incurable[…]