IP6: an endogenous small molecule which promotes DNA repair
IP6, inositol hexaphosphate or phytic acid, is a product of cellular metabolism that binds to[…]
Marine sponges inspire a new family of anticancer agents
A new generation of potential anticancer agents has been developed jointly by three labs in[…]
Cystic fibrosis: organoid technology to identify new antimicrobial therapeutic strategies
Cystic fibrosis is the most common rare genetic disease. In these patients, respiratory infections contribute[…]
How PAXX keeps our DNA in check
Monitoring the integrity of DNA is the function of the many repair systems present in[…]
The organisation of carbohydrates on the surface of Mycobacterium tuberculosis facilitates infection
The bacterium Mycobacterium tuberculosis, the agent of human tuberculosis, has developed different strategies to attenuate[…]
Macrophage infection by fusion with HIV-1-infected T lymphocytes: Catch me to fuse
Although antiretroviral therapies are effective in reducing viral load in HIV-1 infected patients, one of[…]
Thomas Gensollen receives a starting grant from the Fondation pour la Recherche Médicale to launch his research project on inflammatory disorders
Inflammatory bowel disease (IBD) and asthma are chronic inflammatory disorders of the gut and airways,[…]
Could a well-known antidepressant prevent severe forms of COVID-19?
In the context of the emergence of new variants of SARS-CoV-2, increasingly resistant to vaccines[…]
Metal efflux platforms in the membrane of bacteria
Scientists have discovered a novel mechanism of resistance to metal intoxication in macrophages involving mobile[…]
Fight against tuberculosis: the structure of an important target unravelled
Despite its importance as a therapeutic target against tuberculosis, the structure of Pks13 (PolyKetide Synthase[…]